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Iovance Biotherapeutics, Inc.

IOVA · Nasdaq · Published October 11, 2026 · Based on Fri, Oct 9 close IN FOCUS

$14.62 −4.4% from 52-week high · +730.7% from 52-week low

This analysis is based on closing-price data as of October 9, 2026. Whether you're researching how to buy Iovance Biotherapeutics, Inc. stock or you've just opened a brokerage account and are trying to time an entry, here are objective support levels and stop-loss references built from the RSI, MACD and ATR indicators.

Over two years IOVA has turned a long slide from roughly $12 in late 2024 to a $1.76 low into a steep recovery, and it now trades 4.4% below its 52-week high of $15.30 with Mansfield RS vs the Nasdaq Composite at +201.35. The trend was already built before the September 29 guidance gap (bullish moving-average stack since August 7, MACD golden cross September 16), and the week ending October 9 was a test of that gap: an −8.4% session on October 6 and a +9.8% rebound on October 9, both on below-to-average volume. The chart is a strong, extended uptrend — close about 23% above its 20-day average, RSI back above 70 and a bearish RSI divergence flag — so the short-term question is whether the $11.17–$12.78 gap zone keeps holding.

Snapshot as of Oct 9, 2026 close

ItemValueNote
Close$14.62Sep 30 close $14.82 remains the highest close of the 2-year window
52-week high / low$15.30 / $1.76−4.4% / +730.7%; the high is the Sep 29 intraday print
SMA 5 / 20 / 60$13.59 / $11.91 / $8.46Close > SMA5 > SMA20 > SMA60 (stack in place since Aug 7)
Bollinger (20)$15.93 / $11.91 / $7.90Width 67.39% — very wide; close in the upper half of the band
aVWAP 90d (anchor Aug 6, 2026)$9.71Short-term anchor at the August gap; price well above
aVWAP 2y (anchor May 9, 2025)$4.03Long-term anchor near the cycle low
RSI (14)73.18Overbought (>70); bearish RSI divergence flagged
Mansfield RS vs Nasdaq Composite+201.35Outperform, rising; −7.37 vs a week ago, +83.54 vs a month ago
MACD (12,26,9)1.479 / 1.425 / +0.054Golden cross Sep 16; histogram positive but thin
ADX (14)59.38 (90d) / 59.10 (2y)Strong trend
ATR (14)$0.92 (6.27% of price)High volatility — wide daily ranges
OBV 2y / 90dAccumulation / AccumulationBoth above MA20 and rising (MA20 gap 49.02% / 17.06%); no OBV divergence flagged
Volume vs 20d avg0.863x16,970,400 vs 19,660,595 avg; ≈1.27x after adjusting for a 0.681x market median
1× / 2× ATR stop$13.70 / $12.792× ATR reference = −12.5% from close

① Price & Moving Averages

IOVA 90-day price chart with moving averages, Bollinger Bands, aVWAP and Fibonacci levels

The full bullish stack — close above SMA5 ($13.59), SMA20 ($11.91) and SMA60 ($8.46) — has been in place since August 7, and all three averages are rising. The 90-day chart is a staircase: an August 6 gap, a steady September climb from the $8.14 swing low (Sep 10), then the September 29 guidance gap that printed the $15.30 52-week high and a $14.82 close on September 30. The current Fibonacci swing runs from that $8.14 low to the $14.82 high; the October 6–7 dip closed below the 23.6% retracement ($13.24) at $12.96 and $12.92 — just above the top of the unfilled September 29 gap ($11.17–$12.78), with the October 7 intraday low of $12.31 reaching into it — and October 9 closed back at $14.62. The weak point is distance: the close sits about 23% above SMA20 and 73% above SMA60, so even a normal pullback toward the 20-day average would be a large percentage move.

② Volume

IOVA 90-day volume with 20-day average

The two volume spikes that define this advance are the August 6 and September 29 gap days (about 4.5x and 5.6x the 20-day average); both are now outside the latest five sessions. Since then volume has normalized: the October 6 decline came on roughly average volume (about 1.0x), and the October 9 rebound printed 16,970,400 shares, 0.863x its 20-day average. The tape was quiet overall — the median stock in our scan universe traded at 0.681x its own average that day — so relative to the market IOVA's participation was somewhat above normal (≈1.27x), but not the kind of surge that confirms a fresh breakout. Volume on any move through $15.30 is the confirmation to look for.

③ MACD

IOVA 90-day MACD, signal line and histogram

MACD (1.479) has been above its signal line (1.425) since the September 16 golden cross, which came well above zero — a continuation signal rather than an early one. The histogram, however, has shrunk to +0.054: the MACD line rolled over during the October 6–7 dip and came close to the signal line before ticking back up on October 9. That narrowing says upside momentum has slowed after the gap; a cross below the signal line would be the first momentum confirmation of a deeper pause, while a re-widening histogram would mean the October 9 rebound has follow-through.

④ RSI

IOVA 90-day RSI(14) with overbought and oversold zones

RSI(14) is 73.18, back above 70 after cooling into the mid-60s during the October 6–7 dip. The chart tool flags a bearish RSI divergence, with its first reference peak on August 20 (price $8.99, RSI 83.31), set against the higher price highs since. A divergence is a caution flag about thinning momentum, not a top call — it only matters if price follows through by failing below recent support. In a trend this strong, RSI can stay above 70 for weeks; the more useful read is whether dips keep holding above 50.

⑤ Mansfield Relative Strength

IOVA 90-day Mansfield relative strength vs the Nasdaq Composite

Relative strength is the reason IOVA is on this list: Mansfield RS vs the Nasdaq Composite is +201.35, deep in outperform territory with a rising slope. Week over week it eased by 7.37 points (from +208.72) — positive but slowing — while month over month it is up 83.54 points (from +117.82), still accelerating on the longer view. The RS line had already been above zero since spring and was climbing through August and September before the guidance gap; the gap added a step, and the past week gave back part of it. A continued slide in RS while the Nasdaq holds would be the first sign of the leadership fading.

⑥ ATR · ADX

IOVA 90-day ATR(14) and ADX(14)

ADX at 59.38 marks a strong trend, though it has eased slightly from its early-October level. ATR has stepped up to $0.92, or 6.27% of price — the highest reading on this chart, lifted by the gap and the wide October sessions. That volatility sets the risk math: the 1× ATR reference is $13.70 and the 2× ATR reference is $12.79, about 12.5% below the close and almost exactly at the top of the September 29 gap ($12.78). Position sizing has to absorb daily swings of this size.

⑦ OBV

IOVA 90-day on-balance volume with 20-day average

OBV reads accumulation on both timeframes: above its MA20 and rising on the 2-year view (MA20 gap 49.02%) and on the 90-day view (17.06%). On the 90-day chart OBV dipped after the September 30 peak as the October 6 decline subtracted volume, then turned up again with the October 9 rebound, staying above its rising MA20 throughout. No OBV divergence is flagged. Volume flow therefore still supports the trend; a cross of OBV below its MA20 would be the first volume-based sign of distribution.

Bull vs Bear

Bull Case

  • Full bullish stack Close > SMA5 > SMA20 > SMA60 since Aug 7, all averages rising.
  • Mansfield RS +201.35 vs the Nasdaq Composite; leadership was built before the Sep 29 event.
  • The Oct 6–7 dip closed above the Sep 29 gap top ($12.78), and Oct 9 recovered back above the 23.6% retracement ($13.24).
  • OBV in accumulation on both the 2-year and 90-day views; no OBV divergence.
  • ADX 59.38 — a strong, established trend; MACD still above its signal line.
  • Close only 4.4% below the 52-week high; Sep 30's $14.82 is the highest close in two years.

Bear Case

  • Close about 23% above SMA20 and 73% above SMA60 — stretched.
  • RSI 73.18 overbought, with a bearish RSI divergence flagged.
  • MACD histogram has narrowed to +0.054 — momentum slowing after the gap.
  • RS slipped 7.37 points week over week; the gap-driven step is partly fading.
  • ATR 6.27% of price; the 2× ATR reference sits 12.5% below the close.
  • The unfilled Sep 29 gap ($11.17–$12.78) and the $15.30 high box price in on both sides.

Scenarios

ScenarioProbabilityPathTrigger / Invalidation
Range digestion40%Price chops between roughly $12.78 and $15.30 while SMA20 rises toward the price and RSI resets toward 60.Trigger: closes holding above $13.24 with RSI easing. Invalidation: a close below $12.79 (2× ATR).
Continuation30%October 9's rebound extends through the $14.82 close high and the $15.30 52-week high.Trigger: a close above $15.30 on above-average volume and a re-widening MACD histogram. Invalidation: rejection back below $13.70.
Gap fill30%Momentum fades and price works into the Sep 29 gap ($12.78 down to $11.17), near SMA20 ($11.91) and the 50% retracement ($11.48).Trigger: a close below $12.79 with MACD crossing under its signal. Invalidation of the uptrend structure: a close below $11.17.

Key Levels

PriceRoleBasis
$15.30Resistance52-week high (Sep 29 intraday)
$14.82ResistanceSep 30 close / Fibonacci 0% of the swing
$14.62CurrentOct 9 close
$13.24SupportFibonacci 23.6% retracement
$12.79Stop (2× ATR)2× ATR reference; Sep 29 gap top $12.78 just below
$12.27SupportFibonacci 38.2% retracement (inside the gap)
$11.17SupportSep 29 gap bottom

What to Watch

Conclusion

IOVA remains a relative-strength leader — RS +201.35 vs the Nasdaq Composite, a bullish moving-average stack since August 7 and OBV accumulation on both timeframes — and this week's dip closed above the September 29 gap before an October 9 rebound. The chart is stretched, though: close about 23% above SMA20, RSI 73.18 with a bearish divergence flag and a thin MACD histogram, so a period of digestion is as plausible as a push through the $15.30 high. The objective invalidation reference is the 2× ATR level at $12.79; a close below the gap bottom at $11.17 would mean the gap leg has failed.

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This analysis is an educational interpretation of chart data and is not investment advice. Probabilities and levels are subjective estimates; every investment decision, and its outcome, is your own responsibility. Where a stock has moved on a fundamental catalyst, technical signals alone are not a sufficient basis for a purchase decision.

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